When it comes to overall wellness and anti-aging, one compound that has garnered significant attention is Nicotinamide Mononucleotide, or NMN for short. Touted for its potential anti-aging benefits and ability to improve cellular energy, NMN has become the focus of numerous scientific studies and the centerpiece of many anti-aging supplements.
With a rising wave of interest in NMN supplements, it can be overwhelming to sift through the myriad of options available in the market to find the best NMN supplement for your needs.
To help you decide, we’ve reviewed the best NMN supplements for sale. Each of the NMN supplements below were evaluated on a variety of factors including purity, brand reputation, dosage, customer reviews, and additional ingredients.
Best NMN Supplements
- GenF20 Liposomal NMN (Best NMN brand overall)
- Wonderfeel Youngr NMN
- Purovitalis Liposomal NMN
- Omre NMN + Resveratrol
#1. GenF20 Liposomal NMN: Best NMN Brand Overall
We chose GenF20 Liposomal NMN as the best NMN supplement for purity and maximum absorption. This high-quality NMN supplement contains 250 milligrams of 98% pure NMN, which is a dose that’s clinically proven to boost NAD+ levels.
GenF20 guarantees optimal absorption thanks to liposomal, which serves as a delivery mechanism to help your body take full advantage of the potential health benefits of NMN.
Perks of this specific NMN brand include:
- Supports stronger joints
- Strengthens your immune system
- Promotes DNA repair
- Increases energy production
- Improves sleep
- Revs up your metabolism, making it easier to lose weight
- Supports healthy aging and heart health
- Improves mood
- Boosts libido
- Regulates blood pressure
- Eases joint pain
- Stabilizes blood sugar
Using this NMN supplement is easy. Simply take four capsules daily on an empty stomach, and you should see serious results in two to three months.
One reason why we love GenF20 is that the brand is fully transparent about the quality and purity of its NMN supplement. The product undergoes third-party testing to guarantee its efficacy, and customers are welcome to request a Certificate of Authenticity to see the results for themselves. Plus, GenF20 has been a leader in the anti-aging supplement space for more than 20 years, so you know it’s a reputable brand that you can trust.
We were also impressed by the company’s 67-day money-back guarantee. If you try these liposomal NMN capsules and don’t like the results, you can return the unused portion for a full refund with no questions asked.
The odds are good that you’ll love this NMN supplement, though. Just take a look at what some GenF20 customers have to say:
- “Within two days of taking GenF20, I noticed better, deeper sleep. Now I don’t look tired all the time.”
- “I’ve lost belly fat and turned it into muscle.”
- “My hair doesn’t fall out like it used to, and my nails are longer and stronger than before.”
- “I had low energy, couldn’t concentrate, and felt stressed constantly. GenF20 truly saved me.”
For a two-month supply of GenF20, you’ll pay $69.95, and a six-month supply costs $199.95. The 12-month supply is the best deal at $349.95 (you save $129.75). All orders ship free within the United States.
#2. Wonderfeel Youngr NMN: Popular Anti-Aging Supplement With NMN
We picked Wonderfeel Youngr NMN as the best NMN supplement for people seeking a powerful blend of anti-aging ingredients. This brand pairs 450 milligrams of NMN with 50 milligrams of trans resveratrol to help send your NAD levels skyrocketing. NMN and resveratrol are a very effective combo when it comes to supporting brain and heart health.
Along with each dose of NMN, you’ll also get:
- Two milligrams of ergothioneine, an amino acid found in mushrooms that boasts impressive antioxidant benefits
- 20 milligrams of olive fruit extract (40% hydroxytyrosol), a powerful polyphenol that protects the skin and eyes and may even ward off cancer
- 10 micrograms of vitamin D3, which helps with bone and muscle growth
Wonderfeel Youngr’s formula is engineered by Dr. Andrew Salzman from Harvard University. Dr. Salzman is a professor, scientist, and health pioneer known for his research in cancer and cellular health.
Benefits of taking NMN supplements from this brand include:
- Wipes out brain fog for clearer thinking and better cognitive function
- Relief from aches and pains
- Faster recovery from jetlag and hangovers
- Deeper, more restful sleep for proper energy balance
- Helps ward off age-related weight gain
- Improves skin elasticity
- Boosts post-workout recovery
Customers like Wonderfeel Youngr because of its easy-to-take NMN dosage. To use the product, take two capsules in the morning with a healthy fat source, such as avocado or yogurt.
Wonderfeel Youngr NMN is also free from soy, gluten, and GMO (genetically modified) ingredients, which is yet another reason why we chose it as a top NMN supplement for our list. Plus, the capsules are made from vegetable cellulose, making these NMN supplements safe for people with dietary restrictions, such as vegans and vegetarians.
We also like that Wonderfeel Youngr NMN undergoes third-party testing to ensure quality and purity. The company proudly publishes the results of its clinical research studies and lab testing on its website. Plus, it crafts its dietary supplements in cGMP facilities in the U.S., all of which adhere to strict, federally regulated quality controls.
Another reason why we chose this NMN supplement is that it has very positive customer reviews. Customers say:
- “I have fibromyalgia and have had pain in my shoulder for more than 20 years. After taking these NMN pills, that pain is now gone.”
- “I’m 69 years old and have noticed improved skin appearance and texture. My sleep seems to have gotten better as well.”
- “My energy increased after just two weeks. I’m amazed at how much more active I can be.”
A bottle of 60 capsules will cost you $88, which is more expensive than some of the other NMN products we reviewed. However, if you sign up for regular shipments, you’ll pay only $73 (a savings of $15 per bottle).
#3. Purovitalis Liposomal NMN: Effective NMN Capsules for DNA Repair and Metabolism
We selected Purovitalis as the best NMN supplement for people who only want the purest NMN product. Unlike other brands that package their NMN powder in plastic bottles, Purovitalis uses only dark-colored glass bottles to protect its capsules from degradation due to oxygen and light exposure.
Purovitalis is based in the Netherlands and sources all of its ingredients from Europe. Plus, it tests each bath of pure NMN powder for heavy metals and manufactures its NMN in GMP-certified facilities.
Purovitalis recognizes that it’s tough for the body to metabolize NMN by itself. That’s why it only uses liposomal NMN capsules to help your body take advantage of the full NMN dose. These liposomal NMM capsules:
- Dissolve better than other types of capsules
- Prevent the active ingredient from breaking down in stomach acid
- Enhance delivery by binding to cells
Ingredients in these NMN supplements include Longevir NMN, sunflower lecithin, and maltodextrin (a bulking agent). You’ll get 250 milligrams of NMN in each dose.
Purovitalis liposomal NMN supplements offer some impressive optimal health benefits, such as:
- Supports healthy circadian rhythms for better sleep
- Faster recovery after training
- Healthier skin, hair, and nails
- Improved cardio performance
- Stabilized blood sugar
As for the NMN dosage, Purovitalis recommends taking 250 to 1,000 milligrams daily for the best results. Generally, the older you are, the more NMN you’ll need to take. If you’re currently taking any prescription drugs, however, talk to your doctor before you begin taking NMN supplements.
One thing we like about Purovitalis is its Longevity Academy, which teaches you everything you need to know about fighting the effects of aging. On its website, you’ll find plenty of books, videos, and podcasts to educate you throughout your anti-aging journey.
Customer reviews of Purovitalis are very impressive. This NMN product boasts dozens of five-star reviews, with customers saying things like:
- “I’m 40 and have never been an active person. Now I have the energy to work out six days a week.”
- “I started taking NMN supplements because I was concerned about my eyesight. My eyes don’t feel as clouded anymore.”
- “When I take Purovitalis, I don’t feel sluggish, not even after a long day at work.”
One bottle of 30 capsules costs just 35 euros, which is about $38 USD. If you subscribe to regular shipments, you’ll save 10%, and you can also get a 5% discount on your first order if you sign up for the company’s newsletter. All orders ship free.
#4. partiQlar: Nicotinamide Mononucleotide Supplement With 99% Purity
We chose partiQlar pure NMN as the best NMN supplement due to its commitment to quality. The company only sources its ingredients from Effepharm, a facility that strictly follows FDA and USP guidelines to ensure a safe and effective product.
partiQlar says that its NMN supplements contain 99% pure NMN powder, which is higher than many other NMN brands. The company guarantees the product’s purity via third-party testing and makes the results available on its website for all to download.
Health benefits of taking partiQlar pure NMN include:
- Slows and potentially reverses the aging process
- Promotes fuller hair, stronger nails, and better skin elasticity
- Supports brain function
- Improves insulin sensitivity and may help prevent diabetes
- Boosts NAD levels and supports cellular repair
- Improves energy metabolism and can make it easier to lose weight
- Helps you recover faster after workouts
- Can reduce oxidative stress and ward off inflammation in the brain
- Improves memory and may help fend off Alzheimer’s disease and dementia
Each NMN dose of this product gives you a whopping 500 milligrams of NMN to help raise your NAD levels. NMN is the sole ingredient in these NAD precursors, which means the product is free from soy, gluten, GMOs, unnecessary binders, and artificial sweeteners.
Customers rave about this high-purity NMN supplement. Reviewers say:
- “I’m 76 and was sick of feeling tired all the time. Thanks to partiQlar, I feel like I’m young again. This product really does support healthy aging.”
- “I’m a competitive power lifter and partiQlar definitely gives me the boost I need to excel during my workouts.”
- “I love that PartiQlar is 100% guaranteed. I really feel like it made my NAD levels skyrocket.”
A two-month supply of PartiQlar costs $71.99, and for a six-month supply, you’ll pay $53.99 per bottle. The best value is the 12-month supply at $42.49 per bottle. Subscribe to regular shipments for 10% off your order, and you can also get an extra 10% off your first order by signing up for the company’s newsletter.
#5. Omre NMN + Resveratrol: Cellular NAD+ Booster with Pure NMN + Resveratrol
We chose Omre NMN + Resveratrol as one of the best NMN supplements because it’s one of the only brands we’ve seen that includes BioPerine. BioPerine is a form of black pepper extract that’s been shown to increase the bioavailability of resveratrol.
In each NMN dose, you’ll get high-quality ingredients such as:
- 500 milligrams of 98% pure NMN
- 500 milligrams of 98% pure resveratrol
- Five milligrams of BioPerine
Instead of using silicon dioxide or magnesium stearate as a flow agent, Omre uses rice flour (Nu-FLOW), which is plant-based and vegan-friendly.
Benefits of this dietary supplement include:
- Boosts NAD levels to help fight age-related disease
- Increases energy levels throughout the day
- Helps you sleep better
- Supports strong nails and supple, younger-looking skin
The company tests its product via third-party labs and makes every batch in U.S.-based facilities that adhere to strict FDA guidelines for purity and quality.
For the optimal dose of NMN, take two capsules of Omre in the morning with a meal containing healthy fats. Omre doesn’t recommend taking NMN supplements on an empty stomach because your body better absorbs resveratrol in the presence of fat.
Customers have plenty of good things to say about the product, which is another reason why we chose it as one of the best NMN supplements. Reviewers say:
- “This stuff has rocketed me into a new sphere of training that I thought I left behind 35 years ago.”
- “I’m 53 and since taking Omre NMN + Resveratrol, people tell me that I don’t look my age.”
- “I’ve been able to take off weight that I was having trouble losing.”
One bottle of Omre NMN + Resveratrol includes 60 capsules and costs $59.97. If you buy two bottles at once, you’ll pay $113.90. For the biggest savings, you’ll want to buy the three-month supply, which costs $152.92 (a savings of 15%). You can also score a discount by signing up for Omre’s newsletter or subscribing to regular shipments once every 30 days.
What Is NMN?
NMN, or nicotinamide mononucleotide, is a naturally occurring molecule that’s derived from niacin, ribose, nicotinamide, and nicotinamide riboside. It’s also a nucleotide, which makes it one of the building blocks of DNA and RNA.
NMN converts directly to nicotinamide adenine dinucleotide (NAD+), which influences vital bodily functions such as DNA repair. NAD levels naturally drop as the body ages, leading to conditions such as cancer, arthritis, diabetes, and cognitive decline.
It may be possible to boost NAD levels by exercising, eating fewer calories, and maintaining a healthy sleep schedule. Some people also choose to give their bodies a helping hand with NMN supplement products.
NMN is a direct precursor of NAD. Fans of NMN, such as David Sinclair, take these anti-aging supplements to ward off cognitive disease and potentially slow or even reverse the aging process.
NMN supplements work by boosting NAD+ naturally. Benefits of NAD boosters include:
- Increased brain health and protection from neurodegeneration
- Improved liver function, allowing the liver to regenerate
- Better blood flow
- Reduced muscular atrophy
- Reduced inflammation and better immune cell function
- Increased insulin secretion in the pancreas
- Prevention of insulin resistance in adipose tissue
How To Choose the Best NMN Brands
If you’d like to buy NMN supplements but don’t know which to choose, we’re here to help. Here’s how to pick the best NMN supplements for you.
Purity and Quality
To choose the best NMN supplements, look for a brand that guarantees the purity and quality of the NMN molecules in its product. The most reputable brands proudly post this information on their website, where customers can easily find it.
To buy the best supplement, look for high-purity NMN products, such as partiQlar, that boast a purity of at least 99%.
When shopping for the best NMN brands, be sure to choose a product that undergoes third-party testing. Good NMN supplement companies send their products to independent labs to test them for safety, purity, and efficacy.
You should also choose a brand that posts the results of third-party testing on its website. If the company hides its results or makes you jump through hoops to see them, you may want to steer clear of it.
The best NMN supplements won’t do you much good if you can’t keep up with the dosage, so buy a product that’s easy to take. Most of the brands we reviewed recommend taking one or two capsules every morning.
Some suggest taking your supplement on an empty stomach, but others instruct you to take the product with healthy fats, such as avocado, grass-fed butter, or olive oil. This is a good idea if the product contains resveratrol because fat allows your body to metabolize it better.
You should also consider how many milligrams of NMN come with each dose. The less NMN a product contains, the more you’ll need to take to see effects. The best products contain 250 to 500 milligrams of NMN per dose.
Form of Supplement
When looking for the best NMN products for overall health, consider which form of NMN you’d like to take. NMN comes in easy-to-swallow capsules, sublingual NMN tablets, and loose powder. Some brands also combine NMN with other ingredients, as we’ll discuss below.
Additional ingredients are another factor to consider when shopping for the best NMN supplements. As mentioned above, some products contain resveratrol, which has been shown to boost your body’s ability to metabolize NMN. BioPerine, which comes from black pepper extract, is another ingredient that helps your body boost its NAD levels.
Some products include added vitamins, such as vitamins B3 and D3, for more energy, better focus, and improved mood.
If you adhere to a vegan diet, look for products with capsules made from vegetable cellulose.
The best NMN supplements contain no GMO ingredients, soy, gluten, trans fats, or artificial colors.
When you compare NMN supplements, it’s smart to choose a brand that offers a generous return policy. The best brands will allow you to return the unused capsules for a full refund if you decide that you don’t like the product.
Some companies have a return policy of only 30 days, which may not be enough time for you to know whether the product really works for you. The best companies give you two or more months to return the product for a refund. GenF20, for instance, has a 67-day money-back guarantee.
Benefits of NMN Supplements
NMN supplements boost NAD levels, support healthy aging, and may potentially ward off age-related diseases such as cancer, Alzheimer’s, dementia, and diabetes. Other health benefits of NMN supplementation include:
- Improves sleep quality
- Healthier skin, hair, and nails
- More energy at work and school
- Faster workout recovery
- Stabilizes blood sugar
- Improves libido
- Boosts fertility
- Improves insulin sensitivity
- Reduces fat mass and increases lean muscle mass
- Reestablishes mobility in the elderly
- Suppresses age-related weight gain
- Improves eye function
Types of NMN Supplements
You’ll find several different forms of NMN on shelves. Here, we describe some of the most common.
Capsules and tablets are some of the most popular types of NMN supplements, and they’re as easy to find as they are to take. To use them, simply swallow one or two capsules daily. Most brands make their capsules out of vegetable cellulose, so they’re safe for vegans.
Another type of NMN supplement you’ll find is the powdered form. One perk of powder is that it’s much cheaper than capsules. Depending on the brand, you could pay $30 to $50 for a large bag. However, NMN powder has a relatively poor absorption rate compared to other forms.
Sublingual NMN isn’t as common as other types of NMN supplements, but it’s well worth a look. To use these products, just place a lozenge under your tongue.
Research on the bioavailability of sublingual tablets is limited, but some people report feeling a surge of energy minutes after using such products.
Liposomal or Nano NMN
Liposomal NMN is one of the most popular types of NMN, and for good reason. These products contain fatty “shells” called liposomes that protect NMN from degrading in stomach acid. Some researchers think that liposomes increase the absorption of NMN by a factor of three to 10.
However, the liposomal form of NMN is quite expensive. You’ll typically pay about $70 for a one-month supply.
Combined supplements are another type of NMN product that you might want to try. They combine NNM with ingredients such as resveratrol, BioPerine (from black pepper), and vitamin B3. These ingredients may give you more energy, help your body better absorb NMN, and promote feelings of overall well-being.
Where To Buy NMN
One of the best ways to buy NMN is to do so online. This can be a smart choice if you don’t feel like digging through store shelves to find the product you need. Plus, it allows you to easily compare brands and shop for the best deals.
You’ll find quite a few NMN supplements on sites such as Amazon, but it may not be a good idea to purchase your NMN there. That’s because Amazon can be rife with counterfeit products.
These may seem like fantastic deals, but there’s no way to guarantee their safety and effectiveness. At best, such products will do absolutely nothing. At worst, a counterfeit NMN supplement could make you very sick. Not only that, but you’ll likely lose out on a money-back guarantee. That means you may not be able to return the product if you don’t like it.
Instead of heading to third-party websites, it’s better to buy NMN supplements directly from a brand’s website. This way, you know you’ll get exactly what you paid for: a product with high-quality ingredients.
You can also find NMN supplements in some pharmacies and nutrition stores, such as GNC and The Vitamin Shoppe.
Frequently Asked Questions
Why is NAD important?
NAD+ is important because it directly and indirectly influences important cellular functions, including immune function, cellular senescence, chromatin remodeling, and DNA repair. These functions are critical for healthy aging and maintaining metabolic homeostasis.
Your body makes its own NAD+, but it can’t keep up the pace forever. NAD+ levels naturally decrease with age, no matter how much you exercise or how healthy your diet is.
NMN usage is one way to boost NAD availability in your body. That’s because NMN is a direct precursor to NAD, meaning that it helps your body make more of it.
Some foods, such as beef, mushrooms, cucumbers, avocados, cabbage, and broccoli, contain small amounts of NMN. However, you’d have to eat multiple pounds of such foods daily to get enough NMN to increase NAD levels.
This is why NMN supplements can be so helpful. By supplementing, you’ll get much more NMN than you would through diet alone.
Is NMN safe?
According to experts, it’s safe to take up to 1,200 milligrams of NMN per day. So, if you’re wondering, “Are NMN supplements dangerous?” the answer is no, as long as you don’t exceed that dose.
However, it is possible that NMN supplements may interact with certain prescription drugs or other supplements. If you take medication, talk to your doctor before you try NMN.
Are NMN and NR (Nicotinamide Riboside) the same thing?
NMN and NR are chemically identical, which means they have the same molecular structure. However, NMN has an extra phosphate group that NR doesn’t.
The biggest difference between NMN and NR is that NR can enter cells directly while NMN cannot. NMN’s extra phosphate group must be removed before it’s able to enter cells.
Whether you choose an NMN or NR supplement, it’s important to know that you must keep both products in the cold (such as a refrigerator) to keep the molecules from degrading.
Are there any side effects from NMN supplementation?
NMN doesn’t typically cause any side effects, but certain people might experience diarrhea, gas, abdominal pain, and upper respiratory issues. Some may also feel a bit drowsy after taking NMN.
Are NMN powders worth it?
NMN powders are worth it if you don’t get enough NMN in your diet, as most people don’t. If you notice signs of aging, such as a lack of energy, aching joints, memory problems, and hair loss, you could benefit from an NMN supplement.
What’s the recommended dosage for NMN?
There is no single best-recommended dose of NMN because the ideal dose depends on your age. Experts recommend taking 250 to 1,200 milligrams per day. The older you are, the more you’ll need to take.
People younger than 35 years old should start with 250 milligrams and increase the dose to 500 milligrams after two weeks. If you’re older than 35, start with 500 milligrams and increase the dose to 1,000 milligrams.
What brand of NMN does David Sinclair take?
Aging expert David Sinclair doesn’t disclose the exact brand of NMN he takes, but he does say that he takes one gram (1,000 milligrams) of NMN every morning. He also claims to take a stack consisting of:
- Resveratrol, one gram
- Metformin, 800 milligrams
- Quercetin, 500 milligrams
- Fisetin, 500 milligrams
- Trimethylglyicine, 500 to 1,000 milligrams
- Low-dose aspirin, 83 milligrams
- Spermidine, one milligram
- Vitamin D3, 4,000 to 5,000 IU
- Vitamin K2, 180 to 360 micrograms
What is the best form of NMN to take?
The best form of NMN to take is either capsules or sublingual tablets. You may also want to consider trying liposomal NMN. NMN degrades in stomach acid, so some brands use liposomal NMN to protect the molecules and increase their bioavailability to your body.
Is it better to take NMN with resveratrol?
NMN and resveratrol make a good pair because they work together to boost NAD levels in the heart and skeletal muscle. NMN by itself doesn’t significantly raise NAD in the brain, but people who take NMN with resveratrol generally have a big jump in NAD in their brains. The exact reason why this happens is unclear.
Not all NMN supplements contain resveratrol, so be sure to check the ingredient label before buying. Products we reviewed that contain this ingredient include Wonderfeel Youngr NMN and Omre NMN + Resveratrol.
When is the best time to take an NMN supplement?
Most brands recommend that you take an NMN supplement in the morning. Some say that you should take it one hour before eating, although others suggest taking your supplement with healthy fats such as avocado and yogurt.
Is it okay to take NMN every day?
It’s perfectly fine to take an NMN supplement every day, and most brands recommend that you do so. That’s because NMN works best when you take it regularly. NMN needs time to build up in your body, which means you may not see any benefits if you only take it every now and then.
By taking any of the best NMN supplements on our list regularly, you should see at least some effects in two to three weeks. For the most pronounced effects, you may need to take your supplement for a few months.